IntroductionHuman Cytomegalovirus (HCMV) is a betaherpesvirus that causes severe disease in immunocompromised transplant recipients.Immunotherapy with CD8 T cells specific for HCMV Ball - Junior Tops - Jacket antigens presented on HLA class-I molecules is explored as strategy for long-term relief to such patients, but the antiviral effectiveness of
Background: Hemodynamic optimization of unstable patients by means of fluid resuscitation improves patient outcome, but choosing the correct amount of fluid can be difficult.Too little fluid may not ensure adequate perfusion whereas too much fluid is associated with increased mortality.Static parameters are not sufficiently sensitive to detect a re
Lawn Decor Abstract Background PCA3 is a non-coding RNA (ncRNA) that is highly expressed in prostate cancer (PCa) cells, but its functional role is unknown.To investigate its putative function in PCa biology, we used gene expression knockdown by small interference RNA, and also analyzed its involvement in androgen receptor (AR) signaling.Methods LN
Vaccines are highly effective for curbing the spread of SARS-CoV-2 (COVID-19).Yet, millions of Americans remain hesitant about getting vaccinated, jeopardizing our ability to end the COVID-19 pandemic by fueling the spread and development of Watch Bands new variants.We show that brief video-based messages of encouragement addressing specific COVID-
Abstract Background Against a background of pandemic threat posed by SARS and avian H5N1 influenza, this study used deliberative forums to elucidate informed community perspectives on aspects of pandemic planning.Methods Two deliberative forums were carried out with members of the South Australian community.The forums were supported by a qualitativ